The active ingredient in Tadalista 20 is tadalafil. Men are prescribed this medication to treat two prevalent sexual diseases, premature ejaculation and erectile dysfunction. Tadalista 20 should ideally be taken with water. Water is used to swallow the full tablet. Other solvents should be avoided as the medication only reacts readily with water in the bloodstream. It is necessary to take the pill 30 to 60 minutes before sexual activity. Duloxetine in Tadalista 20 works by increasing serotonin levels in the central nervous system, which prolongs and strengthens the control over ejaculation. Take it with or without a meal at a designated time.